Journal article
Fabrication of a Biocompatible Liquid Crystal Graphene Oxide–Gold Nanorods Electro- and Photoactive Interface for Cell Stimulation
D Duc, PR Stoddart, SL McArthur, RMI Kapsa, AF Quigley, M Boyd-Moss, SE Moulton
Advanced Healthcare Materials | WILEY | Published : 2019
Abstract
For decades, electrode–tissue interfaces are pursued to establish electrical stimulation as a reliable means to control neuronal cells behavior. However, spreading of electrical currents in tissues limits its spatial precision. Thus, optical cues, such as near-infrared (NIR) light, are explored as alternatives. Presently, NIR stimulation requires higher energy input than electrical methods despite introduction of light absorbers, e.g., gold nanoparticles. As potential solution, NIR and electrical costimulation are proposed but with limited interfaces capable of sustaining this stimulation technique. Here, a novel electroactive nanocomposite with photoactive properties in the NIR range is con..
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Awarded by Australian National Fabrication Facility
Funding Acknowledgements
This work was supported by Swinburne University of Technology, the ARC Centre of Excellence for Electromaterials Science (ACES) [CE140100012], the ARC Training Centre in Biodevices [IC140100023] and the Australian Research Council Centre of Excellence Scheme. This work was performed in part at the ANFF - Vic Biointerface Engineering Hub (Swinburne University of Technology) and the Materials Node (University of Wollongong) of the Australian National Fabrication Facility (ANFF). A company established under the National Collaborative Research Infrastructure Strategy to provide nano and microfabrication facilities for Australia's researchers. The authors further acknowledge the facilities, the scientific and technical assistance of the RMIT University's Microscopy & Microanalysis Facility, a linked laboratory of the Australian Microscopy & Microanalysis Research Facility. The authors also thank Biofab3D@ACMD - St Vincent's Hospital for their support.